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Nephrology

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Albumin-Corrected Calcium

Approximate total calcium correction when albumin is abnormal.

Formula:

Corrected Calcium = Total Calcium + 0.8 × (4.0 - Albumin)

Interpretation:

Assessment of albumin-corrected calcium.

Units
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Clinical importance
  • Corrected calcium can better reflect active ionized calcium when albumin is abnormal.
  • It supports assessment of parathyroid function.
  • It helps classify hypo- and hypercalcemia in the right clinical context.
  • It is useful for monitoring calcium and vitamin D treatment.
Common causes of hypercalcemia
  • Prolonged immobilization
  • Vitamin D toxicity
  • Malignancy
  • Primary hyperparathyroidism
Common causes of hypocalcemia
  • Malabsorption
  • Kidney dysfunction
  • Vitamin D deficiency
  • Hypoparathyroidism
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